CHAPTER I INTRODUCTION The Philippines is known to be one of the countries in Southeast Asia enzootic for leptospirosis. The National Statistical Coordination Board (NSCB,2008), showed on their 2001 2008 Notifiable Diseases describe Cases that there are 426 total tour of of leptospirosis cases last 2008. However, A total of 690 leptospirosis cases and 36 leptospirosis finishs have been record by the section of Health, most of which are from Metro Manila. (ABS-CBNNews Website,2010).Latest describe incidents were announced by the Department of Health in Union Mindanao region stating that the death toll from leptospirosis infection in the calamity-devastated areas of Cagayan de Oro and Iligan reached 15 while everyplace 400 others were infected (Pasaylo,2012). Leptospirosis is an epizootic distemper of global diffusion cause by members of the genus Leptospira. Leptospires are coiled, very thin, passing motile beingness with hooked ends and two periplasmic flage lla that are used for burrowing the tissue .They are also obligate aerobes, easily cultured, and fundament survive for keen-sighted periods in water or grunge (Levett,2001). Leptospires enter by dint of broken skin, abrasions in the skin or through with(predicate) built-in mucous membranes .
They may also set ahead entry through drinking of contaminated water, through the mouth, throat, or esophagus and when Leptospiremia (presence of leptospires in blood) develops after leptospires gain entry to the consistence ,it subsequently spreads to both the organs. Leptospires multiply in the blood and tissues and green goddess be unaff ectionate from blood and CSF (cerebrospinal ! fluid) during the first 410 days of illness. Leptospires (all forms and types of leptospires) can damage the walls of small blood vas and cause vasculitis, which can lead to hemorrhage and leakage and volcanic eruption of carrels. Leptospires adhere to cell surface and cause cellular toxicity (Vinetz,2001). Nonspecific signs including fever, chills, business organization , conjunctival suffusion, Myalgia of the...If you lack to get a secure essay, order it on our website: BestEssayCheap.com
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