CHAPTER I  INTRODUCTION    The Philippines is known to be one of the countries in Southeast Asia  enzootic for leptospirosis. The National Statistical Coordination Board (NSCB,2008), showed on their   2001  2008   Notifiable Diseases  describe Cases that there  are 426 total  tour of of leptospirosis cases last 2008. However, A total of 690 leptospirosis cases and 36 leptospirosis  finishs have been record by the  section of Health, most of which are from Metro Manila. (ABS-CBNNews Website,2010).Latest  describe incidents were announced by   the Department of Health in  Union Mindanao region stating that the death toll from leptospirosis infection in the calamity-devastated areas of Cagayan de Oro and Iligan reached 15 while  everyplace 400 others were infected (Pasaylo,2012).   Leptospirosis is an epizootic  distemper of global  diffusion cause by members of the genus Leptospira. Leptospires are coiled, very thin,  passing motile  beingness with hooked ends and two periplasmic flage   lla that are used for burrowing the tissue .They are also obligate aerobes, easily cultured, and   fundament survive for  keen-sighted periods in water or  grunge (Levett,2001). Leptospires enter  by dint of broken skin, abrasions in the skin or  through with(predicate)  built-in mucous membranes .

 They may also  set ahead entry through drinking of contaminated water, through the mouth, throat, or esophagus and when Leptospiremia (presence of leptospires in blood) develops after leptospires gain entry to the  consistence ,it   subsequently spreads to  both the organs. Leptospires multiply in the blood and tissues and  green goddess be  unaff   ectionate from blood and CSF (cerebrospinal !   fluid) during the first 410 days of illness. Leptospires (all forms and types of leptospires) can damage the walls of small blood  vas and cause vasculitis, which can lead to hemorrhage and leakage and  volcanic eruption of  carrels. Leptospires adhere to cell surface and cause cellular  toxicity (Vinetz,2001). Nonspecific signs including fever, chills,  business organization , conjunctival suffusion, Myalgia of the...If you  lack to get a  secure essay, order it on our website: 
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